This is one of the most important monastic centers in Epirus which was founded in the early 14th century (1310 to 1320), by Saint Neilos Erihiotis. At a certain point, it functioned as a Secret School and Seminary. The Katholikon was built in the 14th century and was renovated in the 16th century (1568). The walls are decorated with Byzantine frescoes of the 16th and 17th century folklore. The temple was made in 1824.

The Monastery is located in the village of Kokkinolithari and it is one of the most beautiful attractions and the largest pilgrimage of the prefecture of Thesprotia. It has a long history which is intertwined with a large number of legends and traditions. It belongs to Giromeri Monastery since 1667.

The monastery of Agios Minas is celebrated on November 11th and is open for visit all year round.